Week 7 - Definitions

Terms:

• Microsomes
• Signal Recognition Particle 
• BiP (315)

Dictionary: Chapter 11

Microsomes - Fragment of the rough endoplasmic reticulum with associated ribosomes obtained by centrifugation of cells.

http://slideplayer.com/10696140/37/images/21/Figure+11.5+Incorporation+of+secretory+proteins+into+microsomes+%28Part+2%29.jpg

Signal Recognition Particle (SRP) - A ribonucleoprotein that recognizes and targets proteins to be transported to the endoplasmic reticulum in eukaryotes and the plasma membrane in prokaryotes. 

http://oregonstate.edu/instruct/bb451/451material/stryer7/CH30/figure_30_35.jpg

BiP - A chaperone related to HSP70 that binds to elongating polypeptide chains emerging into the endoplasmic reticulum, encouraging its movement into the lumen of the ER during posttranslational translocation. 

https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjpZWeoJKDtMM6x9fEsYVl2p6mlZCM2kVLh6gp0TdkGxg3hmWFwcrw7VyYt_cvDhm4sYyns2P-KXa_0tvDICgxQSViPGdRx2wAGjEb42-1aEupMUI1reMcZSq4iL1AcnPdzOTH-fW2BKQBq/s1600/posttranslational+translocation.jpg